The role of FOXP3 in disease progression in colorectal cancer patients
نویسندگان
چکیده
The transcription factor forkhead box P3 (FOXP3) has been identified as a marker of CD4+CD25+ regulatory T cells and is a key determinant of their immunosuppressive functions. FOXP3 has indeed been shown to limit antitumor immune responses during tumor progression. In addition, by expressing FOXP3, tumor cells may evade effector T-cell responses.
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2013